WHAT ARE FIBROIDS?Fibroids
are muscular tumors that grow in the wall of the uterus (womb). Another
medical term for fibroids is "leiomyoma" (leye-oh-meye-OH-muh) or just
"myoma". Fibroids are almost always benign (not cancerous). Fibroids can
grow as a single tumor, or there can be many of them in the uterus.
They can be as small as an apple seed or as big as a grapefruit. In
unusual cases they can become very large.
WHY SHOULD WOMEN KNOW ABOUT FIBROIDS?About
20 percent to 80 percent of women develop fibroids by the time they
reach age 50. Fibroids are most common in women in their 40s and early
50s. Not all women with fibroids have symptoms. Women who do have
symptoms often find fibroids hard to live with. Some have pain and heavy
menstrual bleeding. Fibroids also can put pressure on the bladder,
causing frequent urination, or the rectum, causing rectal pressure.
Should the fibroids get very large, they can cause the abdomen (stomach
area) to enlarge, making a woman look pregnant.
WHO GETS FIBROIDS?There are factors that can increase a woman's risk of developing fibroids.
AGE- Fibroids become more common as women age, especially during the
30s and 40s through menopause. After menopause, fibroids usually shrink.
FAMILY HISTORY - Having a family member with fibroids increases your
risk. If a woman's mother had fibroids, her risk of having them is about
three times higher than average.
ETHNIC ORIGIN - African-American women are more likely to develop fibroids than white women.
OBESITY - Women who are overweight are at higher risk for fibroids. For
very heavy women, the risk is two to three times greater than average.
EATING HABITS - Eating a lot of red meat (e.g., beef) and ham is linked
with a higher risk of fibroids. Eating plenty of green vegetables seems
to protect women from developing fibroids.
WHERE CAN FIBROIDS GROW?Most fibroids grow in the wall of the uterus. Doctors put them into three groups based on where they grow:
Submucosal (sub-myoo-KOH-zuhl) fibroids grow into the uterine cavity.
Intramural (ihn-truh-MYOOR-uhl) fibroids grow within the wall of the uterus.
Subserosal (sub-suh-ROH-zuhl) fibroids grow on the outside of the uterus.
Some
fibroids grow on stalks that grow out from the surface of the uterus or
into the cavity of the uterus. They might look like mushrooms. These
are called pedunculated (pih-DUHN-kyoo-lay-ted) fibroids.
WHAT ARE THE SYMPTOMS OF FIBROIDS?Most fibroids do not cause any symptoms, but some women with fibroids can have :
*Heavy bleeding (which can be heavy enough to cause anemia) or painful periods
*Feeling of fullness in the pelvic area (lower stomach area)
*Enlargement of the lower abdomen
*Frequent urination
*Pain during sex
*Lower back pain
*Complications during pregnancy and labor, including a six-time greater risk of cesarean section
*Reproductive problems, such as infertility, which is very rare.
WHAT CAUSES FIBROIDS?No
one knows for sure what causes fibroids. Researchers think that more
than one factor could play a role. These factors could be:
*Hormonal (affected by estrogen and progesterone levels)
*Genetic (runs in families)
Because
no one knows for sure what causes fibroids, we also don't know what
causes them to grow or shrink. We do know that they are under hormonal
control — both estrogen and progesterone. They grow rapidly during
pregnancy, when hormone levels are high. They shrink when anti-hormone
medication is used. They also stop growing or shrink once a woman
reaches menopause.
CAN FIBROIDS TURN TO CANCER?Fibroids
are almost always benign (not cancerous). Rarely (less than one in
1,000) a cancerous fibroid will occur. This is called leiomyosarcoma
(leye-oh-meye-oh-sar-KOH-muh). Doctors think that these cancers do not
arise from an already-existing fibroid. Having fibroids does not
increase the risk of developing a cancerous fibroid. Having fibroids
also does not increase a woman's chances of getting other forms of
cancer in the uterus.
WHAT IF I BECOME PREGNANT AND HAVE FIBROIDS?Women
who have fibroids are more likely to have problems during pregnancy and
delivery. This doesn't mean there will be problems. Most women with
fibroids have normal pregnancies. The most common problems seen in women
with fibroids are:
*Cesarean section. The risk of needing a c-section is six times greater for women with fibroids.
*Baby
is breech. The baby is not positioned well for vaginal delivery.
Meaning that the head of the baby is pointing towards your chest and not
the birth canal.
*Labor fails to progress.
*Placental
abruption. The placenta breaks away from the wall of the uterus before
delivery. When this happens, the fetus does not get enough oxygen and
may die if no medical intervention is made.
*Preterm delivery.
Talk
to your obstetrician if you have fibroids and become pregnant. All
obstetricians have experience dealing with fibroids and pregnancy. Most
women who have fibroids and become pregnant do not need to see an OB who
deals with high-risk pregnancies.
HOW DO I KNOW FOR SURE THAT I HAVE FIBROIDS?Your
doctor may find that you have fibroids when you see her or him for a
regular pelvic exam to check your uterus, ovaries, and vagina. The
doctor can feel the fibroid with her or his fingers during an ordinary
pelvic exam, as a (usually painless) lump or mass on the uterus. Often, a
doctor will describe how small or how large the fibroids are by
comparing their size to the size your uterus would be if you were
pregnant. For example, you may be told that your fibroids have made your
uterus the size it would be if you were 16 weeks pregnant. Or the
fibroid might be compared to fruits, nuts, or a ball, such as a grape or
an orange, an acorn or a walnut, or a golf ball or a volleyball.
Your
doctor can do imaging tests to confirm that you have fibroids. These
are tests that create a "picture" of the inside of your body without
surgery. These tests might include:
*Ultrasound – Uses sound
waves to produce the picture. The ultrasound probe can be placed on the
abdomen or it can be placed inside the vagina to make the picture.
*Magnetic resonance imaging (MRI) – Uses magnets and radio waves to produce the picture.
*X-rays – Uses a form of radiation to see into the body and produce the picture.
*Computerized Tomography scan (CT scan) – Takes many X-ray pictures of the body from different angles for a more complete image.
*Hysterosalpingogram
(hiss-tur-oh-sal-PIN-juh-gram) (HSG) or sonohysterogram
(soh-noh-HISS-tur-oh-gram) – An HSG involves injecting x-ray dye into
the uterus and taking x-ray pictures. A sonohysterogram involves
injecting water into the uterus and making ultrasound pictures.
You might also need surgery to know for sure if you have fibroids. There are two types of surgery to do this:
*Laparoscopy
(lap-ar-OSS-koh-pee) – The doctor inserts a long, thin scope into a
tiny incision made in or near the navel. The scope has a bright light
and a camera. This allows the doctor to view the uterus and other organs
on a monitor during the procedure. Pictures also can be made.
*Hysteroscopy
(hiss-tur-OSS-koh-pee) – The doctor passes a long, thin scope with a
light through the vagina and cervix into the uterus. No incision is
needed. The doctor can look inside the uterus for fibroids and other
problems, such as polyps. A camera also can be used with the scope.
WHAT QUESTIONS SHOULD I ASK MY DOCTOR IF I HAVE FIBROIDS?How many fibroids do I have?
What size is my fibroid(s)?
Where is my fibroid(s) located (outer surface, inner surface, or in the wall of the uterus)?
Can I expect the fibroid(s) to grow larger?
How rapidly have they grown (if they were known about already)?
How will I know if the fibroid(s) is growing larger?
What problems can the fibroid(s) cause?
What tests or imaging studies are best for keeping track of the growth of my fibroids?
What are my treatment options if my fibroid(s) becomes a problem?
What are your views on treating fibroids with a hysterectomy versus other types of treatments?
A
second opinion is always a good idea if your doctor has not answered
your questions completely or does not seem to be meeting your needs.
FDA warning on power morcellators in treatment for uterine fibroids
If
your doctor recommends a hysterectomy or myomectomy to treat your
uterine fibroids, ask your doctor if a power morcellator will be used.
Power morcellators break uterine fibroids into small pieces to remove
them more easily. Recently, the FDA warned against the use of power
morcellators for most women. This is because uterine tissue may contain
undiagnosed cancer. While breaking up the uterine tissue, power
morcellators can spread an undiagnosed cancer to other parts of the body
without your doctor knowing it. Most uterine fibroids are not
cancerous, but there is no way to know for sure until the fibroids are
removed and tested.
HOW ARE FIBROIDS TREATED?Most women with fibroids do not have any symptoms. For women who do have symptoms, there are treatments that can help.
Talk
with your doctor about the best way to treat your fibroids. She or he
will consider many things before helping you choose a treatment. Some of
these things include:
*Whether or not you are having symptoms from the fibroids
*If you might want to become pregnant in the future
*The size of the fibroids
*The location of the fibroids
*Your age and how close to menopause you might be.
If
you have fibroids but do not have any symptoms, you may not need
treatment. Your doctor will check during your regular exams to see if
they have grown.
MEDICATIONS If you have fibroids
and have mild symptoms, your doctor may suggest taking medication.
Over-the-counter drugs such as ibuprofen or acetaminophen can be used
for mild pain. If you have heavy bleeding during your period, taking an
iron supplement can keep you from getting anemia or correct it if you
already are anemic.
Several drugs commonly used for birth control
can be prescribed to help control symptoms of fibroids. Low-dose birth
control pills do not make fibroids grow and can help control heavy
bleeding. The same is true of progesterone-like injections (e.g.,
Depo-Provera®). An IUD (intrauterine device) called Mirena® contains a
small amount of progesterone-like medication, which can be used to
control heavy bleeding as well as for birth control.
Other drugs
used to treat fibroids are "gonadotropin releasing hormone agonists"
(GnRHa). The one most commonly used is Lupron®. These drugs, given by
injection, nasal spray, or implanted, can shrink your fibroids
especially when they are not so big.
Sometimes they are used
before surgery to make fibroids easier to remove. Side effects of GnRHas
can include hot flashes, depression, not being able to sleep, decreased
sex drive, and joint pain.
Most women tolerate GnRHas quite
well. Most women do not get a period when taking GnRHas. This can be a
big relief to women who have heavy bleeding. It also allows women with
anemia to recover to a normal blood count. GnRHas can cause bone
thinning, so their use is generally limited to six months or less.
These
drugs also are very expensive, and some insurance companies will cover
only some or none of the cost. GnRHas offer temporary relief from the
symptoms of fibroids; once you stop taking the drugs, the fibroids often
grow back quickly, making Surgery the best treatment option.
SURGERYIf you have fibroids with moderate or severe symptoms, surgery may be the best way to treat them. Here are the options:
(1).
Myomectomy (meye-oh-MEK-tuh-mee) – Surgery to remove fibroids without
taking out the healthy tissue of the uterus. It is best for women who
wish to have children after treatment for their fibroids or who wish to
keep their uterus for other reasons. You can become pregnant after
myomectomy. But if your fibroids were imbedded deeply in the uterus, you
might need a cesarean section to deliver. Myomectomy can be performed
in many ways. It can be major surgery (involving cutting into the
abdomen) or performed with laparoscopy or hysteroscopy. The type of
surgery that can be done depends on the type, size, and location of the
fibroids. After myomectomy new fibroids can grow and cause trouble
later. All of the possible risks of surgery are true for myomectomy. The
risks depend on how extensive the surgery is.
(2). Hysterectomy
(hiss-tur-EK-tuh-mee) – Surgery to remove the uterus. This surgery is
the only sure way to cure uterine fibroids. Fibroids are the most common
reason that hysterectomy is performed. This surgery is used when a
woman's fibroids are large, if she has heavy bleeding, is either near or
past menopause, or does not want children. If the fibroids are large, a
woman may need a hysterectomy that involves cutting into the abdomen to
remove the uterus. If the fibroids are smaller, the doctor may be able
to reach the uterus through the vagina, instead of making a cut in the
abdomen. In some cases hysterectomy can be performed through the
laparoscope. Removal of the ovaries and the cervix at the time of
hysterectomy is usually optional. Women whose ovaries are not removed do
not go into menopause at the time of hysterectomy. Hysterectomy is a
major surgery. Although hysterectomy is usually quite safe, it does
carry a significant risk of complications. Recovery from hysterectomy
usually takes several weeks.
(3). Endometrial Ablation
(en-doh-MEE-tree-uhl uh-BLAY-shuhn) – The lining of the uterus is
removed or destroyed to control very heavy bleeding. This can be done
with laser, wire loops, boiling water, electric current, microwaves,
freezing, and other methods. This procedure usually is considered minor
surgery. It can be done on an outpatient basis or even in a doctor's
office. Complications can occur, but are uncommon with most of the
methods. Most people recover quickly. About half of women who have this
procedure have no more menstrual bleeding. About three in 10 women have
much lighter bleeding. But, a woman cannot have children after this
surgery.
(4). Myolysis (meye-OL-uh-siss) – A needle is inserted
into the fibroids, usually guided by laparoscopy, and electric current
or freezing is used to destroy the fibroids.
(5). Uterine Fibroid
Embolization (UFE), or Uterine Artery Embolization (UAE) – A thin tube
is thread into the blood vessels that supply blood to the fibroid. Then,
tiny plastic or gel particles are injected into the blood vessels. This
blocks the blood supply to the fibroid, causing it to shrink. UFE can
be an outpatient or inpatient procedure. Complications, including early
menopause, are uncommon but can occur. Studies suggest fibroids are not
likely to grow back after UFE, but more long-term research is needed.
Not all fibroids can be treated with UFE. The best candidates for UFE
are women who:
Have fibroids that are causing heavy bleeding
Have fibroids that are causing pain or pressing on the bladder or rectum
Don't want to have a hysterectomy
Don't want to have children in the future.
WHAT NEW TREATMENTS ARE AVAILABLE FOR UTERINE FIBROIDS?The following methods are not yet standard treatments, so your doctor may not offer them or health insurance may not cover them.
1. Radiofrequency ablation uses heat to destroy fibroid tissue without
harming surrounding normal uterine tissue. The fibroids remain inside
the uterus but shrink in size. Most women go home the same day and can
return to normal activities within a few days.
2. Anti-hormonal drugs may provide symptom relief without bone-thinning side effects.
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information on our website is provided by the U.S. federal government
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and may be reproduced without permission, though citation of each source
is appreciated.
Steve Eisinger, M.D., F.A.C.O.G.